Despite a goal by Luis Diaz, the Reds were held to a draw and seized the lead, but Manchester City might defeat Newcastle to extend their advantage to three points.
Was it today that Liverpool's night fantasies came to an end?
Reds fans still have optimism of finishing the season with four trophies in their possession. However, they suffered a setback at the top of the Premier League.
Their 1-1 draw with Tottenham moved them one point ahead of Manchester City with one game still to play. However, when you look at the overall picture, it was more of a loss.
Pep Guardiola's squad has a chance to win against Newcastle on Sunday afternoon at the Etihad Stadium to expand their lead to three points and give them a significant edge in the race for the Premier League title.
After Son Heung-56th-minute min's goal, Jürgen Klopp's pupils gave all they had on the field until Luis Diaz leveled the score 16 minutes into the second half.
The Anfield Road crowd erupted in delight as the home side attempted to salvage a point, but the decisive goal failed to materialize.
Who would have imagined that Tottenham would have such a significant impact on the Premier League championship race? Antonio Conte's club, who has taken six points away from Manchester City this season, grabbed four points away from the Reds.
By creating issues at Anfield, they may have jeopardized Liverpool's chances of winning the Premier League. They set the way for Liverpool to win the league in February with their victory against Manchester City.
It was a really interesting game. Relentless, fast-paced, and competitive in its intensity and tempo. Liverpool applied pressure and was assertive. Diaz performed well and deserved to be awarded the goal.
Meanwhile, Tottenham defended the penalty area superbly, with to outstanding efforts from Cristian Romero and Ben Davies, and then Son created counter-threats by exploiting the locations of Harry Kane and Ryan Sessegnon in the Tottenham box.
It's true that the Londoners had a chance to win the game if they had performed better in the last moments of the game.
Liverpool advanced to the Champions League final by defeating Villarreal in Spain, and they had a fantastic week after their victory against Newcastle.
They were there to see Real Madrid pull off a miracle against Manchester City at the Bernabeu.
On Saturday night, they had wanted to come away with a victory at Anfield, but that didn't happen.
Klopp set himself a mission at the conclusion of the game and welcomed the Kop stands with enthusiasm in order to keep the supporters' spirits up.
"It has the potential to be a very significant landmark," former Red midfielder Didi Hamann said of Klopp's appointment. You can see where he's coming from, even if it seems to some to be a case of naive optimism.
After all, they're in the lead for the time being and will be expecting City to lose either on Sunday or at home to West Ham, Wolves, or Aston Villa in the coming weeks.
However, even if that does not happen, Klopp's squad can still be happy of the work they have done thus far.
After looking to be out of the picture in January, they have at the very least joined the championship hunt.
They are still focused on achieving triumphs. They will attempt to win the FA Cup for the first time since 2006 next weekend, and they will meet Real Madrid in the Champions League final later this month, with the goal of painting Paris red.
Anfield is experiencing a period of prosperity.
Of course, none of this precludes the possibility that the outcome of the Tottenham game may be detrimental. The crew that was always able to find a solution was unable to do so this time. Anfield served as a site of somber reflection rather than joy this time.
Liverpool should hold out hope for a comeback from this point on, against Manchester City...