The omicron strain is spreading rapidly throughout the country. Some people have been infected with the corona virus twice. Even if reinfection does occur, how significant is the risk?

COVID-19 : Why you can get infected with Corona several times
COVID-19 Reinfection


The corona virus has infected tens of thousands of Germans every day since Omicron began spreading. There have been more and more successes. Re-infection, as it is often known, is prevented by many people believing this. The reality, on the other hand, is a little more complicated. After surviving a corona infection, it is possible to re-infect yourself. What's going on here? At a glance, the most pressing issues are addressed.

How big is the risk of a renewed corona infection?

After surviving an infection with Sars-CoV-2, the likelihood that you will get the virus again depends on a number of variables. Examples include prior health issues and vaccines as well as one's own immune system. Researchers have also discovered a link between recurrent Covid 19 infections and the progression of the illness. Prof. Martina Prelog says that when a corona infection is mild or asymptomatic, just a few antibodies are produced or the antibody concentration drops rapidly. She has a doctorate in immunology from the University Hospital Würzburg and is board certified in pediatrics and youth medicine.

Another thing to keep in mind: "Neutralizing antibodies are also associated to a high antibody concentration. For the coronavirus to enter the cell, it requires a virus surface protein that these antibodies can specifically recognize. As a result, antibodies inhibit viruses from invading cells effectively "Martina Prelog explains this.

Re-infection is prevented by a high level of antibodies?

Besides B cells, the immune system also relies on T cells. The coronavirus causes cytotoxic T lymphocytes to seek out and kill infected cells in order to stop the virus from spreading further in the body. The innate immune system and antibody-producing B cells are assisted in the elimination of the virus by helper T cells. According to the immunologist: "The T cell response to Sars-CoV-2watch was quite strong even in those with moderate courses and low antibody concentrations. With Covid-19, they are effectively protected from serious infections." For those with a healthy immune system, the T cells are usually good enough to prevent severe illness, which means that whether persons who had a moderate course are more likely to become reinfected relies not only on antibody concentrations but also on T cells.

How often does reinfection occur?

According to a study released by the UK Health Security Agency at the end of March, the pandemic has resulted in more than 804,000 new cases of infection in the United Kingdom. Two positive corona tests at least 90 days apart are considered a re-infection. In response to a question from the star, the Robert Koch Institute said that it doesn't keep track of reinfections.

Are there any Omikron variants that might infect me if I have previously been infected with Omikron?

If you've had Omicron in the last few months, you're more than likely at risk of contracting the same variety again. According to Prelog, the omicron subvariant BA.2 has been reported to cause re-infections after infection with the subvariant BA.1. Researchers in Denmark analyzed 1.8 million Covid cases in a preprint. After a prior BA.1 infection, 47 people were re-infected with BA.2 by genome sequencing. After infection with subvariant BA.1 in younger, unvaccinated persons, BA.2 might be re-infected, according to the research.


What protection does vaccination or recovery offer?

According to a research from the United States, people who have recovered and are also completely vaccinated have a greater chance of becoming sick again than those who are unvaccinated.


A two-year study monitored the immune responses of patients who had received the vaccine and then recovered. Martina Prelog was also a member of the research team. Most importantly, the immune system must have encountered the coronavirus at least three times in order to develop a strong level of immunity. Covid-19 protection implies that a major illness with all of its personal and societal implications (Long Covid, secondary infections, complications, mortality, overburdening of the health-care system), explains Prelog. An perfect "hybrid immunity," i.e., having been infected and then vaccinated twice (although it's also possible to be infected and then vaccinated).


That the immune system has enough time to pick the finest B cells for antibody production is critical to immunity, according to the immunologist. In patients with a healthy immune system, the antibody protection lasts at least six months. In order to provide long-term protection against Sars-CoV-2, long-lived plasma cells that produce antibodies against Sars-CoV-2 are necessary." They'd also supply us with years, if not our whole lives, worth of immune system defenses. Prelog notes that long-term research are presently underway to see whether this is the case with Sars-CoV-2.


Re-infection of the corona generally has a lesser effect?

People who have a strong immune system have a more tolerable infection with Covid-19. The variation and the timing of reinfection are also factors to consider. "A six-month period following a Sars-CoV-2 infection (with alpha or delta) saw the average protection against reinfection fall from 85 percent to zero to 27 percent, according to data from England. T-cells, on the other hand, have a tendency to protect against more serious cases, but not an infection "Prelog is reporting on this. In part, this is due to the fact that so many individuals have been immunized that their immunity has improved, making it more difficult for them to get the disease.


What role does the omicron variant play in reinfection?

According to research, Omicron does not create as powerful an immune response as Delta. Martina Prelog, an immunologist, adds that mild or asymptomatic omicron courses are especially dangerous. Re-infections have increased when the omicron variety was introduced. This is shown by the UK's statistics: When the omicron variation predominated (20 December to 20 March 2022), the probability of reinfection was around ten times greater than when the delta variant predominated (17 May to 19 December). 2021), according to British government data (Office for National Statistics). A similar image is painted by a research based on Qatari data. Only 56% of people are protected against re-infection by Omikron because they already had an illness. As a point of contrast, Delta has a 92% rating.



Previous Post Next Post